A great-great granddaughter of Nampeyo of Hano, Darlene is a descendant through Nampeyo's eldest daughter Annie Healing and Annie's eldest daughter Rachel Namingha. Her mother is Ruth James, sister of Dextra Quotskuyva, Eleanor Lucas and Priscilla Namingha.
Darlene learned to make pottery from her aunts, Priscilla and Dextra. Her designs are all painted with bee-weed (black) and then traditionally fired to create "fire clouds" on the clay surface.
Darlene's pottery can be found in museums throughout the Southwest. She has also won ribbons at events such as the Santa Fe Indian Market and the Heard Museum Indian Art Fair.